Librela for humans?

Jacqui-S

Moderator
Location
Fife, Scotland
I've come across a few things in the last few weeks that may give hope for the OA suffers.

The use of MABs (injected) and GEPANTs (oral) for the treatment of migraine - they are monoclonal antibodies targeting calcitonin related peptides (don't ask me any more......) and beginning to creep into use in secondary care neurology clinics.

Also some studies are showing that Semaglutide (that elusive diabetic injection @kateincornwall ) has some anti-inflammatory benefits that help with OA pain, over and above the benefit you would expect just from weight loss.

Just really putting it here to say that things are in the pipeline. The MABs seem to be possibly useful for a huge range of diseases. You never know.
 
Location
Norfolk
That’s interesting @Jacqui-S .

I saw the consultant at the trauma clinic about 10 days ago, he told me my knee wasn’t bad enough to warrant any nhs treatment. I asked about keyhole surgery (arthroscopy?) and he acted as if I’d asked him to give me his life savings, more or less told me to go away and put up with it. Lovely bloke :shake: .
 

Jacqui-S

Moderator
Location
Fife, Scotland
That’s interesting @Jacqui-S .

I saw the consultant at the trauma clinic about 10 days ago, he told me my knee wasn’t bad enough to warrant any nhs treatment. I asked about keyhole surgery (arthroscopy?) and he acted as if I’d asked him to give me his life savings, more or less told me to go away and put up with it. Lovely bloke :shake: .
Urgh, orthopods aren't known for their bedside manner.
Having said that, evidence is lacking for the benefit of such things as steroid injections and arthroscopic "scraping" for knee pain so it has virtually disappeared outside the private sector.
Lack of evidence and lack of money....
Physio is the main treatment recommendation these days :hmm:
 
That’s interesting @Jacqui-S .

I saw the consultant at the trauma clinic about 10 days ago, he told me my knee wasn’t bad enough to warrant any nhs treatment. I asked about keyhole surgery (arthroscopy?) and he acted as if I’d asked him to give me his life savings, more or less told me to go away and put up with it. Lovely bloke :shake: .
Wot a w**ker. I've seen 1 NHS guy and another private specialist about my knee issues. Although it went as expected both were clear about my options and very nice. They explained my lack of options and difficulties which I expected but were kind and understanding.
 

HAH

Moderator
Location
Devon, UK
It's disappointing isn’t it how little interest there seems to be in some conditions. Although I feel it’s different if you’re male.
Well this is sadly true, increasingly recognized in medical research and backed up by a lot of evidence (I’d strongly recommend Invisible Women by Caroline Criado Perez).

Another vote here for physiotherapy for pain issues. Definitely worth a try if you’ve not already been down that road.
 
I'm in pain all the time all over. I lived with it for a long time. The constant falls EDS and other serious medical issues have contributed to this. I can't have a lot of pain relief because of other medical issues. It's hard but I found being pushy and asking help. I live with it the best I can and find ways to help myself. Physio and changing the way I do things help but it's overwhelming some times. I get very tired
 
Location
Norfolk
Well this is sadly true, increasingly recognized in medical research and backed up by a lot of evidence (I’d strongly recommend Invisible Women by Caroline Criado Perez).

Another vote here for physiotherapy for pain issues. Definitely worth a try if you’ve not already been down that road.
Thank you for that - I have reserved it to read on my Kobo.
 
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Jacqui-S

Moderator
Location
Fife, Scotland
I just checked our surgery website, it says:

”There is a highly trained physiotherapist working with our surgery.”

No other details, so I guess I’ll have to ring them after the bank holiday.
Quite possibly a First Contact Physio from that description. A real boon, make use of them.
If not, still try see someone, but there a re good self-directed exercises both on NHS inform and Versus Arthritis.
 
I'm in pain all the time all over. I lived with it for a long time. The constant falls EDS and other serious medical issues have contributed to this. I can't have a lot of pain relief because of other medical issues. It's hard but I found being pushy and asking help. I live with it the best I can and find ways to help myself. Physio and changing the way I do things help but it's overwhelming some times. I get very tired
I'm really sorry to hear this. Living in constant pain is horrible. You are very brave Sarah.
 
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