Galliprant for arthritis

[Jacqui-S]

I know this has been mentioned a few times on the forum and the snatches I saw seemed quite positive.
Just looking for opinions on it for those who have used it for a while
With Lilly we have gone through the usual NSAIDs, Pardale V (co-codamol), Tramadol, Gabapentin, Cartrophen, Librella.....None have made much of a difference in recent years.
She is currently on Paracetamol 500mg bd with the higher strength Yumove and golden paste, and are retrying gabapentin given that probably she has as much problem from spinal stenosis (with stool incontinence) as she does her hips and elbows now.
Unfortunately after 2 or 3 of the 300mg gaba she could barely walk (tolerated it a few years back ) so I'm cautiously retitrating from 100mg bd. Not dreadfully hopeful but we're giving it a go.
Next step would probably be the Galliprant.
Your thoughts welcome.....

 

[Cath]

So sorry about poor Lilly, but I have never used Galliprant. Hope you can find something to help her

 

[kateincornwall]

So sorry that you have tried everything for dear Lilly without lasting success . Nelly has gabapentin from time to time, plus pardale as needed , YuMove and golden paste , I hope you can find something positive for Lilly xx

 

[Anne123]

I know this has been mentioned a few times on the forum and the snatches I saw seemed quite positive.
Just looking for opinions on it for those who have used it for a while
With Lilly we have gone through the usual NSAIDs, Pardale V (co-codamol), Tramadol, Gabapentin, Cartrophen, Librella.....None have made much of a difference in recent years.
She is currently on Paracetamol 500mg bd with the higher strength Yumove and golden paste, and are retrying gabapentin given that probably she has as much problem from spinal stenosis (with stool incontinence) as she does her hips and elbows now.
Unfortunately after 2 or 3 of the 300mg gaba she could barely walk (tolerated it a few years back ) so I'm cautiously retitrating from 100mg bd. Not dreadfully hopeful but we're giving it a go.
Next step would probably be the Galliprant.
Your thoughts welcome.....

Finn gets gabapentine 2x150mg, onsior1x40mg, librela and paracetamol. He is on a max dosis what he can tolerate. He weighs 32 kg

 

[Jacqui-S]

onsior1x40mg

Lilly was on Previcox for many years. She had to stop it when she was on lupus treatment and when she restarted it afterwards it didn't help

 

[Stacia]

Rourke had a ketamine injection once a month when he had his Librella. He was also on gabapentin and paracetamol. I think we tried Galliprant way back but it caused him to bleed internally.

 

[Selina27]

I don't have any experience of this so I can't comment but I hope you can find something to keep our Queen comfortable xx

 

[HAH]

I know this has been mentioned a few times on the forum and the snatches I saw seemed quite positive.
Just looking for opinions on it for those who have used it for a while
With Lilly we have gone through the usual NSAIDs, Pardale V (co-codamol), Tramadol, Gabapentin, Cartrophen, Librella.....None have made much of a difference in recent years.
She is currently on Paracetamol 500mg bd with the higher strength Yumove and golden paste, and are retrying gabapentin given that probably she has as much problem from spinal stenosis (with stool incontinence) as she does her hips and elbows now.
Unfortunately after 2 or 3 of the 300mg gaba she could barely walk (tolerated it a few years back ) so I'm cautiously retitrating from 100mg bd. Not dreadfully hopeful but we're giving it a go.
Next step would probably be the Galliprant.
Your thoughts welcome.....

We’ve tried all sorts with Kipper including gabapentin, which didn’t seem to do much as far as I remember (it was a long time ago). I think the evidence in still unclear on gabapentin’s value in therapeutic pain relief for dogs, it’s more effective as an anti anxiety med - (Gabapentin and Pregabalin as Analgesics - NDSR). Galliprant is more likely to help with pain control as one of the newer NSAIDs that acts directly on a pain receptor called E4 which deals with inflammation and pain associated with OA, so there are fewer side effects like GI issues.
Is your vet helpful? We’ve recently started seeing a new vet for Kipper’s treatment to get a fresh pair of eyes on his OA, and it’s given us a lot of new ideas already.

 

[Jacqui-S]

Is your vet helpful?

Hmm. Vets are mixed. A recent one was talking in terms of time to PTS. I'm giving them the benefit of misinterpreting my discussion of how difficult I find the nocturnal incontinence.
Lilly still likes to get out and walk and as far as I can tell is happy and enjoys life . Of course still eats well, and may possibly have that and a possible walk as her main foci in life.

 

[Jacqui-S]

there are fewer side effects like GI issues.

After reading the PIL, I must admit the GI side effects of Galliprant have made me pause. At the moment most of her incontinent stool is pick-upable......
I have to just remind myself that every drug known to humankind has diarrhoea AND constipation as possible side effects.

 

[Stacia]

Lilly still likes to get out and walk and as far as I can tell is happy and enjoys life . Of course still eats well, and may possibly have that and a possible walk as her main foci in life.

I think while they have quality of life, Lilly appears happy, enjoys walks and food, then they cope. Try Ketamine.

 

[Jacqui-S]

Ketamine

Never been on offer. Think I mentioned it once....not used here I don't think.

 

[Granca]

Lilly still likes to get out and walk and as far as I can tell is happy and enjoys life . Of course still eats well, and may possibly have that and a possible walk as her main foci in life.

Those are all positives, aren't they. I don't have any experience of arthritis treatment for dogs, but years ago a vet told me that once an animal loses interest in eating or drinking it may be time to move on from treatment. It seems that Lilly still enjoys quality of life, as Sonia has said, so it's difficult to know why a vet would have suggested PTS at this stage. I hope you find something that suits her.

 

[Granca]

PS Have you tried hydrotherapy - the treadmill version?

 

[Jacqui-S]

PS Have you tried hydrotherapy - the treadmill version?

Pool based hydrotherapy fortnightly since she was a year old....


Not sure there are any local treadmills.
Wearing her new swim pants

 

[MellowYellow]

It's so hard isn't it Jaq? I can't help with any information regarding painkillers I'm afraid, but I do think that as long as Lilly seems happy, enjoys her walks, food, and cuddles, and as long as you can deal with the incontinence, then all is ok - especially since we are now coming into the warmer weather, which I think is a bit easier on the joints. I really feel for you though.

 

[Parodius]

My previous lab Billie was on Galliprant for several years for her arthritis and it did help. I don’t specifically remember it causing any tummy issues, but she was on a few other medications for other things too so it would have been tricky to pin down. The main problem I had was it had to be given on an empty stomach an hour before food. This meant delaying her breakfast which she was definitely not on board with! Hope you find something that works for Lily.

 

[Jacqui-S]

Thanks @Parodius
I did think the empty tummy thing may be a challenge too.

 

[M.F.]

This podcast popped up in my app a few days ago: How to reverse arthritis in 8 weeks | Dr. Tamiko Katsumoto

The doctor is a Stanford professor. The podcast title is a bit click-baity, but the info in the podcast is useful.

While it’s difficult to know whether what affects humans can equally affect dogs, I thought the advice could be generalised to all: eat more wholefoods, eat more plants, eat more roughage, eat more omega 3 (preferably from algae or small fish, but not big fish), eat less red meat, eat less refined food.

I forget what you’re feeding Lily? But I wonder whether she could benefit from some dietary changes or additions? As another option, while you try to find meds that will work for her?

 

[Cath]

Has anyone here used Cimalgex 80 mg for their dog's arthritis? Just got back from France and our french vet has given us some to try with Fred. He doesn't take it all the time, (Fred not the vet) just when he is bad and then only for 4 days.