Poppy seizures - medicating with Pexion

MellowYellow

MellowYellow

Well, Poppy had another fit on Wednesday afternoon, so I was at the vets with her on Thursday for blood tests. The tests came back all clear, so there is nothing else going on.

We are going to start the Pexion tomorrow. I'll start another thread and let you know how we get on with it. Keep your fingers crossed for us!
 
M

M.F.

Have you started the meds? I hope all is going well. It can take a few days/weeks for her to get used to the meds. Do they increase appetite? Snowie never drooled until he started the KBr. It apparently affects the satiety centre in the brain. I have no idea what Pexion does.

Will you be testing for blood levels of the therapeutic dose? Snowie’s went sky high. He had to be on 1/10th of the recommended dose to get the correct therapeutic blood levels. The specialist vet blamed us for overdosing him, but it turned out it was because we feed a raw diet, which is much lower in salt than kibble, and the salt affects how much KBr stays in the blood stream. I had mentioned this to the specialist vet initially, but he’d dismissed my concerns. Just mentioning this all in case you experience similar. Best of luck! Hopefully the Pexion will help Poppy be seizure free. xxx
 
MellowYellow

MellowYellow

We started the Pexion yesterday, and she seemed happy after the first and second dose, which is 400mg twice a day. Today after the morning dose she seemed agitated, and had what seemed like a mini-fit (shivering, lip-licking, eye flicking; but no spasms) that only lasted a minute or two. She was rather hyper on her walk this morning, and is now asleep. Still keen on her food, but so far her appetite doesn't seem any greater than usual (it is always prodigious...).

We're going to give it a week to see how it goes and then chat to the vet again. According to the paperwork, the side effects can differ from sleepiness to heightened arousal, from satiety to increased greediness... but the side effects are apparently lower than with phenobarbital and should desist quite quickly.

My poor girl...
 
M

M.F.

I recall now that Snowie was hyper crazy agitated and desperate for food in the first week or two (I forget exactly how long) of starting the meds. It was so distressing. Of course we gave him food all the time because we were so upset and I guess we found the act of feeding him to be nurturing (He put on 4kg!)—we felt so bad about his condition, about how crazy he went. We were told he’d calm down. Or have a seizure. We were terrified of the latter. I don’t recall if he calmed down, but clearly he wasn’t right, which is why our regular vet did the blood tests. Thank goodness she did! I’d hate to think what the effects of long-term overdosing would’ve done.

Poor Poppy. I’m guessing it must feel weird to be medicated. Hopefully the desired effect will kick in soon.
 
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