Just back from the Wakefield vet now. He was also lovely. He mentioned several possible causes for Joy's symptoms and said that although she looked very poorly, much of that was because she was sedated with the Methadone and although there was the possibility that this was 'something sinister' he felt that that would be the least likely diagnosis. He agreed that a CT scan was needed, will do it in the morning and ring me with the results and a way forward. He said that she was clearly normally a fit and healthy dog, youth is on her side and he feels optimistic that this will be something treatable. I've been awake since 4.30 and on tenterhooks all day. (Am normally a very calm person) Going to heat the remains of Saturday's cauliflower cheese (my faithful comfort food) in the microwave, pour a glass of wine even though it's only Monday, reply to texts from anxious friends and family, and see if I can find something mindless to watch on TV. That shouldn't be difficult! Again, thanks everyone for your support. It's a massive help. Never underestimate the power of a Labrador lover!